Advertisement

The Case for Synthetic Injectables

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribers receive full online access to your subscription and archive of back issues up to and including 2002.

      Content published before 2002 is available via pay-per-view purchase only.

      Subscribe:

      Subscribe to Facial Plastic Surgery Clinics
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Wilson Y.
        • Ellis D.
        Permanent soft tissue fillers.
        Facial Plast Surg. 2011; 27: 540-546
      1. ASPS. ASPS National Clearinghouse of Plastic Surgery Procedural Statistics. Plastic Surgery Statistics Report. 2013. Available at: http://www.plasticsurgery.org/news/plastic-surgery-statistics/2013. Accessed February 25, 2015.

        • Glogau R.
        Fillers: from the past to the future.
        Semin Cutan Med Surg. 2012; 31: 78-87
        • Fulton J.
        • Caperton C.
        The optimal filler: immediate and long-term results with emulsified silicone (1,000 centistokes) with cross-linked hyaluronic acid.
        J Drugs Dermatol. 2012; 11: 1336-1341
      2. Alcon. [Package insert]. Silikon 1000. Ft. Worth, TX: 2013.

        • Hexsel S.
        • de Morais M.
        Management of complications of injectable silicone.
        Facial Plast Surg. 2014; 30: 623-627
        • Orentreich D.
        • Leone A.
        A case of HIV-associated facial lipoatrophy treated with 1000-cs liquid injectable silicone.
        Dermatol Surg. 2004; 30: 548-551
        • Webster R.
        • Hamdan U.
        • Gaunt J.
        • et al.
        Rhinoplastic revisions with liquid silicone.
        Arch Otolaryngol Head Neck Surg. 1986; 112: 269-276
        • Webster R.
        • Gaunt J.
        • Hamdan U.
        • et al.
        Injectable silicone for facial soft-tissue augmentation.
        Arch Otolaryngol Head Neck Surg. 1986; 112: 290-296
        • Duffy D.
        Liquid silicone for soft tissue augmentation.
        Dermatol Surg. 2005; 31: 1530-1541
      3. FDA. “Off-Label” and investigational use of marketed drugs, biologics, and medical devices: information sheet. 2014.

        • Jones D.
        • Carruthers A.
        • Orentreich D.
        • et al.
        Highly purified 1000-cSt silicone oil for treatment of human immunodeficiency virus-associated facial lipoatrophy: an open pilot trial.
        Dermatol Surg. 2004; 30: 1279-1286
        • Ellis L.
        • Cohen J.
        • High W.
        Granulomatous reaction to silicone injection.
        J Clin Aesthet Dermatol. 2012; 5: 44-47
        • Hevia O.
        Six-year experience using 1,000-centistoke silicone oil in 916 patients for soft-tissue augmentation in a private practice setting.
        Dermatol Surg. 2009; 25: 1646-1652
        • Moscona R.
        • Fodor L.
        A retrospective study on liquid injectable silicone for lip augmentation: long-term results and patient satisfaction.
        J Plast Reconstr Aesthet Surg. 2010; 63: 1694-1698
        • Jacinto S.
        Ten-year experience using injectable silicone oil for soft tissue augmentation in the Philippines.
        Dermatol Surg. 2005; 31: 1550-1554
        • Zappi E.
        • Barnett J.
        • Zappi M.
        • et al.
        The long-term host response to liquid silicone injected during soft tissue augmentation procedures: a microscopic appraisal.
        Dermatol Surg. 2007; 33: S186-S192
        • Schwartzfarb E.
        • Hametti J.
        • Romanelli P.
        • et al.
        Foreign body granuloma formation secondary to silicone injection.
        Dermatol Online J. 2008; 14: 20
        • Rapaport M.
        • Vinnik C.
        • Zarem H.
        Injectable silicone: cause of facial nodules, cellulitis, ulceration, and migration.
        Aesthetic Plast Surg. 1996; 20: 267-276
        • Ledon J.
        • Savas J.
        • Yang S.
        • et al.
        Inflammatory nodules following soft tissue filler use: a review of causative agents, pathology, and treatment options.
        Am J Clin Dermatol. 2013; 14: 401-411
        • Beer K.
        Delayed onset nodules from liquid injectable silicone: report of a case, evaluation of associated histopathology and results of treatment with minocycline and celocoxib.
        J Drugs Dermatol. 2009; 8: 952-954
        • Achauer B.
        A serious complication following medical-grade silicone injection of the face.
        Plast Reconstr Surg. 1983; 71: 251-254
        • Anastassov G.
        • Schulhof S.
        • Lumerman H.
        Complications after facial contour augmentation with injectable silicone. Diagnosis and treatment. Report of a severe case.
        Int J Oral Maxillofac Surg. 2008; 37: 955-960
        • Funt D.
        • Pavicic T.
        Dermal fillers in aesthetics: an overview of adverse events and treatment approaches.
        Plast Surg Nurs. 2015; 35: 13-32
        • DeLorenzi C.
        Complications of injectable fillers, part 2: vascular complications.
        Aesthet Surg J. 2014; 34: 584-600
        • Prather C.
        • Jones D.
        Liquid injectable silicone for soft tissue augmentation.
        Dermatol Ther. 2006; 19: 159-168
        • Requena C.
        • Izquierdo M.
        • Navarro M.
        • et al.
        Adverse reactions to injectable aesthetic microimplants.
        Am J Dermatopathol. 2001; 23: 197-202
        • Cohen S.
        • Berner C.
        • Mariono B.
        • et al.
        Five-year safety and efficacy of a novel polymethyl-methacrylate aesthetic soft tissue filler for the correction of nasolabial folds.
        Dermatol Surg. 2007; 33: S222-S230
        • Lemperle G.
        • Knapp T.
        • Sadick N.
        • et al.
        ArteFill Permanent injectable for soft tissue augmentation: I. mechanism of action and injection techniques.
        Aesthetic Plast Surg. 2010; 34: 287-289
        • Rose A.E.
        Therapeutic update on acne scarring.
        J Drugs Dermatol. 2014; 13: 651-654
        • Piacquadio D.
        • Smith S.
        • Anderson R.
        A comparison of commercially available polymethylmethacrylate-based soft tissue fillers.
        Dermatol Surg. 2008; 34: S48-S52
        • Karnik J.
        • Baumann L.
        • Bruce S.
        • et al.
        A double-blind, randomized, multicenter, controlled trial of suspended polymethylmethcrylate microspheres for the correction of atrophic facial acne scars.
        J Am Acad Dermatol. 2014; 71: 77-83
        • Hilinski J.
        • Cohen S.
        Soft tissue augmentation with ArteFill.
        Facial Plast Surg. 2009; 25: 114-119
      4. Suneva. Bellafill instructions for use. 2014.

      5. Suneva. Bellafill skin test instructions for use. 2014.

      6. Suneva. Suneva before and after photo taking guide. 2014.

        • Duffy D.
        The silicone conundrum: a battle of anecdotes.
        Dermatol Surg. 2002; 28: 590-595